Microbe Weaponry
Bacteria and fungi use “weaponry” against other microbes and against the immune system to gain or maintain control of a specific area.
This can be divided into:
Weapons - toxins and enzymes that are released to kill or inhibit the function of other microbes and immune cells.
Protective armour – biofilm, which is secreted as a shield or fortress that cannot be penetrated by immune cells (or by antibiotics).
By removing the damaging toxins and enzymes, the immune cells regain their strength and abilities.
By disrupting the shielding biofilm, the immune cells can enter the fortress and remove unwanted microbes.
The actions of MPPT
Do NOT rely on antibiotics, which mean that MPPT will not be limited by antibiotic resistance issues and will not contribute to the generation of new resistant strains.
Do NOT rely on chemical action to kill cells, which means that MPPT - unlike antiseptics and Manuka honey - is not poisonous to human and animal cells and will not impede cell growth and regeneration.
SertaSil is based on micropore particle technology (MPPT), which consists of fine particles full of narrow pores.
Schematic drawing of the mode-of-action of MPPT.
|
The particles
This results in:
This provides a quicker and more efficient way to remove wound infections.
The following data show that this is actually what is happening:
The effects on wound healing are:
Effects of MPPT application at 24 hours on Pseudomonas aeruginosa biofilm. The biofilm cultures were photographed and analysed when they were 48 hours old. |
---|
Antimicrobial | Cytotoxic to human and animal cells | Balances the microbiome |
Days to non-infected wound (mean±SD)* |
|
---|---|---|---|---|
Antibiotics | + |
- |
- |
7.0 ± 1.2 |
Antiseptics | + |
+ |
- |
8.0 ± 1.1 |
MPPT | - |
- |
+ |
3.0 ± 0.9 |
Comparison of antibiotics, antiseptics and MPPT. *Data from Bilyayeva et al. (2017). The number of days to reach a non-infected wound, i.e. free of necrosis, pus and fibrinogenous thickenings, were recorded for MPPT (n=88), a topical antibiotic (gentamicin) (n=90) and an antiseptic (iodine combined with DMSO) (n=88).
The comparison shows: